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Researcher receives $5.5M grant from National Institute of Health

By Ashley McGinnis, Medical Center Communications

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Published: Wednesday, November 12, 2008

Updated: Saturday, June 20, 2009

Dr. E. Antonio Chiocca of The Ohio State University Medical Center has received a $5.5 million dollar grant over five years from the National Institutes of Health to develop a more potent oncolytic virus as a treatment of brain cancer.

Chiocca, chair of neurosurgery at the James Cancer Hospital and Solove Research Institute, and his team of researchers at the Ohio State University Comprehensive Cancer Center will be working on the development of a biologic agent as a new treatment for brain cancer that may one day be used in human clinical trials.

Oncolytic viruses are a new example of the ability of viruses to infect tumor cells, multiply, destroy and spread to other tumor cells. Researchers at Ohio State's Comprehensive Cancer Center have developed and published preclinical results on a new and more potent oncolytic virus, and this grant will allow them to build on their previous research.

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